DATE: 3RD SEPTEMBER, 2015
TIME: 5.30 – 7.30PM
VENUE: ALOFT KUALA LUMPUR SENTRAL KUALA LUMPUR
What is Pyrroluria and Pyrrole Disorder
Pyrrole disorder is an abnormality of heme metabolism causing an excess production of hydroxyhemoppyrrolin-2-one (HPL), commonly called pyrroles, which are excreted into the urine (Pyrroluria). Pyrroles attract and trap zinc and vitamin B6 which have been absorbed from the diet. These complexes are subsequently excreted into the urine resulting in functional deficiency of zinc and vitamin B6. There are associated changes in fatty acid metabolism leading to low levels of arachidonic acid (an omega-6 fatty acid). The presence of Pyrroluria can have a profound effect on production of neurotransmitters, hence poor mental and physical health, and is associated with severe mood swings, high anxiety, and depression. Pyrrole Disorder was first discovered in relation to schizophrenia.